Sulfamethoxazole / Trimethoprim

How should you use this medication?
Take this medicine by mouth with water. Take it as directed on the prescription label at the same time every day, 12 hours apart. Do not cut, crush or chew this medicine. Swallow the capsules whole. Do not skip doses. You can take it with or without food. You should always take it the same way. Keep taking it unless your health care provider tells you to stop. Do not take the medicine with grapefruit juice. Talk to your health care provider about the use of this medicine in children. While it may be prescribed for children for selected conditions, precautions do apply.

What are the possible side effects of this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
chest pain
heartbeat rhythm changes (trouble breathing; chest pain; dizziness; fast, irregular heartbeat; feeling faint or lightheaded, falls)
high blood sugar (increased hunger, thirst or urination; unusually weak or tired, blurry vision)
high potassium levels (chest pain; fast, irregular heartbeat; muscle weakness)
increase in blood pressure
infection (fever, chills, cough, sore throat, pain or trouble passing urine)
kidney injury (trouble passing urine or change in the amount of urine)
low red blood cell counts (trouble breathing; feeling faint; lightheaded, falls; unusually weak or tired)
low magnesium levels (fast, irregular heartbeat; muscle cramp or pain; muscle weakness; tremors; seizures)
low phosphorus levels (loss of appetite, muscle weakness)
nervous system problem (headache, confusion, seizures, changes in vision, changes in behavior, coma, or tremors)
pain, tingling, numbness in the hands or feet

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

constipation
diarrhea
edema (sudden weight gain; swelling of the ankles, feet, hands or other unusual swelling)
stomach pain
trouble sleeping

What may interact with this medicine?
Our pharmacists will check to see if this medication will cause any interactions with the information in your profile.
Do not take this medicine with any of the following medications:

astemizole
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
cidofovir
cisapride
cyclosporine
dronedarone
droperidol
grapefruit juice
grepafloxacin
live virus vaccines
mesoridazine
pimozide
probucol
ombitasvir; paritaprevir; ritonavir
saquinavir
thioridazine
ziprasidone This medicine may also interact with the following medications:
alcohol and medicines that contain alcohol
amiodarone
bromocriptine
certain antibiotics like aminoglycosides, chloramphenicol, clarithromycin, erythromycin, rifabutin, rifampin, troleandomycin
certain antivirals for HIV or hepatitis
certain calcium channel blockers like diltiazem, nicardipine, nifedipine, verapamil
certain medicines for fungal infections like amphotericin B, caspofungin, clotrimazole
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
certain medicines for stomach problems like antacids, cimetidine, famotidine, lansoprazole, metoclopramide, omeprazole
certain supplements that contain schisandra sphenanthera extracts
cisplatin
danazol
diuretics
ethinyl estradiol
ganciclovir
nefazodone
other medicines that prolong the QT interval (an abnormal heart rhythm)
sirolimus
St. John’s wort
steroid medicines like prednisone, cortisone, methylprednisone
vaccines