Learn About The Benefits Of Sermorelin To Boost Natural HGH Levels
Sermorelin Reported Benefits
Studies have shown stimulating HGH secretion with sermorelin may produce the following benefits:
- Revitalize sex drive and performance
- Restore skin elasticity, thickness and texture
- Increase lean muscle mass
- Decrease body fat
- Protect and restore cognitive health
- Improve sleep quality
What Is Sermorelin?
Sermorelin, also known as GRF 1‐29 or Geref, is a peptide hormone and analog of naturally-occurring growth hormone-releasing hormone (GHRH). A drug analog is a substance that is similar to another compound. Sermorelin consists of the first 29 amino acid sequence in internally-made growth hormone.
How Does Semorelin WorK?
Sermorelin binds to the GHRH receptor and mimics its effects, which is to stimulate the pituitary gland to release natural growth hormone.
Growth hormone peaks in puberty and naturally begins declining in our 30s. But low growth hormone is not just linked to age. Some adults and children are born with or develop medical conditions that cause growth hormone deficiency.
Sermorelin may be prescribed to treat growth hormone deficiency or as part of an overall adult active aging program.
What Does Growth Hormone Do?
Growth hormone is made naturally in the anterior of the pituitary gland. It assists in the development of muscle, tissue, the somatic nervous system and helps regulate metabolism.
Growth hormone secretions begins to wane after age 30. Additionally, studies show obesity,1 lack of exercise and a poor diet can inhibit growth hormone secretion.
Lower growth hormone levels are associated with aging (decreased muscle mass, cognitive decline), increased body fat and diminished sleep quality.2
Sermorelin may help overcome those barriers and help forge a path to better health and active aging.
Is Sermorelin The Same As HGH?
No, sermorelin is not the same as natural (endogenous) HGH. It also should not be confused with recombinant Human Growth Hormone (rhGH).
rhGH is a lab-synthesized replica of HGH. rhGH is FDA-approved to treat growth hormone deficiency in adults and children and wasting from certain diseases such as HIV.
rhGH works by adding growth hormone to the body rather than stimulating its release. rhGH use is illegal in the US for any other purpose than its FDA-approved indications.
Growth hormone secretagogues like sermorelin may be legally prescribed for active aging and other potential benefits of increased growth hormone.
What Are Peptides?
Peptides are short chains of amino acids as opposed to proteins which are long chains of amino acids. Proteins are multiple peptides held together by peptide bonds. The unique amino acid sequences in each peptide defines its function. Different arrangements of peptides define each protein’s role.
What Is the Difference Between GH And IGF-1?
Growth hormone and IGF-1 are both growth hormones that work interdependently. The pituitary gland secretes GH, then growth hormone triggers the synthesis of IGF-1, mainly (about 80%) in the liver but also in bone (about 20%).
IGF-1 modulates the effects of growth hormone and plays a key role in chondrogenesis (bone development).
GH has anti-insulin-like effects while IGF-1 has insulin-like effects. When IGF-1 and HG levels are balanced they help maintain homeostasis of blood sugar levels.
1 Salvatori, R. Growth hormone deficiency in patients with obesity. Endocrine 49, 304–306 (2015). https://doi.org/10.1007/s12020-015-0571-4
2 Garcia JM, Merriam GR, Kargi AY. Growth Hormone in Aging. [Updated 2019 Oct 7]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279163/
These statements have not been evaluated by the Food and Drug Administration (FDA). This drug is not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise, nutritional supplement program, using this drug, and/or any prescription or OTC product during pregnancy or if you have a serious medical condition.
This product is made by a GoodPill Rx partner, a 3rd party licensed, sterile compounding pharmacy.