PT-141 Bremelanotide Nasal Spray


Now the newest FDA-approved libido booster PT-141 (Bremelanotide) is available in a convenient, fast-acting nasal spray from GoodPill Rx. FDA-approved to treat Hypoactive Sexual Desire Disorder (HSDD) in women, some studies show PT-141 treated men with Erectile Dysfunction (ED) and significantly improved erections in men without ED. Find out more about this new peptide!

Please note: We cannot provide telemedicine for ED in LA. We cannot offer this medication in Iowa

Prescription Product: We will ask for your prescription information after checkout.

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PT-141 Offers New Way To Treat Sexual Dysfunction In Men And Women

PT-141 Bremelanotide in the form of injection is FDA-approved to treat HSDD in women, but the peptide’s affect was originally discovered in men. While researching a drug to darken skin, researchers noticed that men got spontaneous erections.

Studies on intranasal administration of PT-141 reported the spray has the same impact as the injection.

An article published in The Journal Nature on the effect of PT-141 nasal spray in with ED and men without ED, showed the effects of PT-141 nasal were “clinically significant”. Both study groups achieved erections when using the PT-141. Depending on physician’s recommendation, bottle may contain up to 8 doses.

What Is PT-141?

PT-141 is an agonist at melanocortin receptors. This means it activates the receptors, causing a response. Melanocortin receptors control sexual function, impact appetite, and immunity, among other physiologic actions.

PT-141 offers promise treating sexual dysfunction in men and women who do not have success with the PDE5 inhibitors Viagra (sildenafil) and Cialis (tadalafil) or can’t take sildenafil or tadalafil for health reasons.

How PT-141 Works

PT-141 is a peptide drug that affects neurotransmitters in the brain called melanocortins. It is not known exactly how PT-141 can cause erections in men and increase women’s libido and sexual satisfaction.

What Is the Difference Between PT-141 And Cialis And Viagra?

PT-141’s main works in the brain, while Cialis (tadalafil) and Viagra (sildenafil) essentially impact blood vessels.

How Do PDE5 Inhibitors Work?

Inhibiting, or blocking, the enzyme phosphodiesterase 5 (PDE5), slows the breakdown of the molecule cGMP. With cGMP still active, the smooth muscles in the penis relax or stay relaxed longer. When the muscles relax, blood vessels open to increase blood flow. This is called vasodilation.

Studies show PDE5 inhibitors may have the same effect in premenopausal2 and postmenopausal women. 2

They increase blood flow to the vagina and clitoris, which boosts libido, increases vaginal lubrication and improves sexual satisfaction. 2,3

Again, not all men and women experience success with PDE5 inhibitors. The same is true for PT-141.

Having these medications that function differently expands sexual dysfunction treatment opportunities for men and women.


1 Diamond, L., Earle, D., Rosen, R. et al. Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction. Int J Impot Res 16, 51–59 (2004).

2Caruso, Salvatore & Intelisano, Giorgia & Lupo, Lorenzo & Agnello, Carmela. (2001). Premenopausal women affected by sexual arousal disorder treated with sildenafil: A double-blind, cross-over, placebo-controlled study. BJOG : an international journal of obstetrics and gynaecology. doi: 108. 623-8. 10.1016/S0306-5456(00)00143-1

3 Alatas E, Yagci AB. The effect of sildenafil citrate on uterine and clitoral arterial blood flow in postmenopausal women. MedGenMed. 2004;6(4):51. Published 2004 Oct 13. The effect of sildenafil citrate on uterine and clitoral arterial blood flow in postmenopausal women.

These statements have not been evaluated by the Food and Drug Administration (FDA). Please consult your physician before starting any exercise or nutritional supplement program before using this or any products if you are pregnant or have a serious medical condition.

This product is made by a GoodPill Rx partner, a 3rd party licensed, sterile compounding pharmacy.

Weight 1 lbs


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