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Common 30-Day Supply: 30

Pregnenolone is the first sex hormone in a chain of transformations that result in the creation of progesterone, testosterone, estrogen and the other sex hormones. Hormone Replacement Therapy with bioidentical pregnenolone may help improve brain function and help prevent osteoporosis and other bone diseases. 1

Compounded Pregnenolone For Affordable, Custom bHRT

The widespread belief that women have no choice but to accept menopause symptoms and its health risks robs women of a fulfilling life postmenopause. Learn about all of your options and take control of your hormones!

What Is Hormone Balancing?

Hormone Replacement Therapy (HRT) is a process in which externally-made hormones are introduced to the body to restore hormonal balance.

What Is Pregnenolone?

Pregnenolone is the precursor to the other steroid sex hormones in the body. This means that pregnenolone is the first substance in the chain of metabolic transformations (steroidogenesis) that lead to the creation of the other sex hormones. The body synthesizes pregnenolone from cholesterol.

Why Does Pregnenolone Do?

Pregnenolone’s importance in the body is not just limited to role in steroidogenesis. Studies show it has neuroprotective2 and osteolytic (related to bones) protective properties.1 Pregnenolone may be prescribed to prevent cognitive decline1 and as an adjunct medication in schizophrenia treatment.2


Bioidentical Hormone Replacement Therapy (bHRT) is HRT but with substances that are molecular and structural matches to internally-made hormones. HRT, without the “b” in front, may refer to the use of nonidentical hormones.

What is Compounded Medicine?

Compounded medications are made by experts who develop recipes specifically for each patient based on their medical condition and needs. Compounded prescriptions are prepared in small batches and do not require commercial fillers and preservatives that industrial pharmaceuticals require for a long shelf life.

Another bonus: Custom-compounded medications may cost up to 50% to 75% less than commercial prescriptions.

Why Should I Buy Compounded Medicine from GoodPill Rx?

With the benefit of personalized medicine at affordable prices, GoodPill Rx’s solutions provide relief for your mind as well as your body. Private, free shipping with the convenience of auto refills and online medical consultations help you continue your bHRT.

This product is made by a GoodPill Rx partner, a 3rd party licensed, sterile compounding pharmacy.

These statements have not been evaluated by the Food and Drug Administration (FDA). Please consult your physician before starting any exercise or nutritional supplement program before using this or any products if you are pregnant or have a serious medical condition.


1 Sun, X., Zhang, C., Gho, H. et al. Pregnenolone Inhibits Osteoclast Differentiation and Protects Against Lipopolysaccharide-Induced Inflammatory Bone Destruction and Ovariectomy-Induced Bone Loss. Front Pharmacol. 2020;11:360. Published 2020 Mar 27. doi:10.3389/fphar.2020.00360

2 Murugan, S., Jakka, P., Namani, S., et al. The neurosteroid pregnenolone promotes degradation of key proteins in the innate immune signaling to suppress inflammation. The Journal of Biological Chemistry doi: 10.1074/jbc.RA118.005543

Weight 1 kg


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