How should you use this medication?
Take this drug by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this drug. Swallow the tablets whole. Some tablets need to be taken on an empty stomach. Ask your pharmacist or health care provider if you have any questions. Keep taking it unless your health care provider tells you to stop. Do not take this drug with grapefruit juice. Talk to your health care provider about the use of this drug in children. Special care may be needed.
What are the possible side effects of this medicine?
Side effects that you should report to your doctor or health care provider as soon as possible:
allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
heart attack (trouble breathing; pain or tightness in the chest, neck, back or arms; unusually weak or tired)
heart failure (trouble breathing; fast, irregular heartbeat; sudden weight gain; swelling of the ankles, feet, hands; unusually weak or tired)
low blood pressure (dizziness; feeling faint or lightheaded, falls; unusually weak or tired) Side effects that usually do not require medical attention (report to your doctor or health care provider if they continue or are bothersome):
bloating
changes in emotions or moods
constipation
facial flushing
headache
nasal congestion (like runny or stuffy nose)
nausea
stomach pain
Show all possible side effects
What may interact with this medicine?
Our pharmacists will check to see if this medication will cause any interactions with the information in your profile.
Do not take this medicine with any of the following medications:
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
lumacaftor; ivacaftor
rifabutin
rifampin
rifapentine
St. John’s Wort This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for blood pressure
certain medicines for diabetes
certain medicines for erectile dysfunction
certain medicines for fungal infections like ketoconazole, fluconazole, and itraconazole
certain medicines for irregular heart beat like flecainide and quinidine
certain medicines that treat or prevent blood clots like warfarin
clarithromycin
digoxin
dolasetron
erythromycin
fluoxetine
grapefruit juice
local or general anesthetics
nefazodone
orlistat
quinupristin; dalfopristin
sirolimus
stomach acid blockers like cimetidine, ranitidine, omeprazole, or pantoprazole
tacrolimus
valproic acid
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