How should you use this medication?
Take this medicine by mouth. Take it as directed on the prescription label at the same time every day. You can take it with or without food. If it upsets your stomach, take it with food. Do not use it more often than directed. There may be unused or extra doses in the bottle after you finish your treatment. Talk to your health care provider if you have questions about your dose. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your health care provider about the use of this medicine in children. Special care may be needed.
Patients over 65 years of age may have a stronger reaction and need a smaller dose.
What are the possible side effects of this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
bleeding (bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose)
blood clot (chest pain; shortness of breath; pain, swelling, or warmth in the leg)
general ill feeling or flu-like symptoms
high potassium levels (chest pain; fast, irregular heartbeat; muscle weakness)
kidney injury (trouble passing urine or change in the amount of urine)
light-colored stool
liver injury (dark yellow or brown urine; general ill feeling or flu-like symptoms; loss of appetite, right upper belly pain; unusually weak or tired, yellowing of the eyes or skin)
low red blood cell counts (trouble breathing; feeling faint; lightheaded, falls; unusually weak or tired)
rash, fever, and swollen lymph nodes
redness, blistering, peeling, or loosening of the skin, including inside the mouth
stroke (changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination) Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation
diarrhea
dizziness
gas
headache
nausea, vomiting
Show all possible side effects
What may interact with this medicine?
Our pharmacists will check to see if this medication will cause any interactions with the information in your profile.
Do not take this medicine with any of the following medications:
cidofovir
ketorolac This medicine may also interact with the following medications:
aspirin and aspirin-like medicines
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, apixaban, dabigatran, rivaroxaban
cyclosporine
diuretics
fluconazole
lithium
methotrexate
other NSAIDs, medicines for pain and inflammation, like ibuprofen and naproxen
pemetrexed
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