Diclofenac Sodium Delayed Release (DR)

How should you use this medication?
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medication. Swallow the tablets whole. You can take this medication with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your care team about the use of this medication in children. Special care may be needed. Patients over 65 years of age may have a stronger reaction and need a smaller dose.

What are the possible side effects of this medicine?
Side effects that you should report to your care team as soon as possible:

Allergic reactions-skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Bleeding-bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
Heart attack-pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
Heart failure-shortness of breath, swelling of ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
Increase in blood pressure
Kidney injury-decrease in the amount of urine, swelling of the ankles, hands, or feet
Liver injury-right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
Rash, fever, and swollen lymph nodes
Redness, blistering, peeling, or loosening of the skin, including inside the mouth
Stroke-sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Headache
Loss of appetite
Nausea
Upset stomach

What may interact with this medicine?
Our pharmacists will check to see if this medication will cause any interactions with the information in your profile.
Do not take this medication with any of the following:

Cidofovir
Ketorolac
Methotrexate This medication may also interact with the following:
Alcohol
Aspirin and aspirin like medications
Cyclosporine
Diuretics
Lithium
Medications for high blood pressure
Medications for osteoporosis
Medications that affect platelets
Medications that treat or prevent blood clots like warfarin
NSAIDs, medications for pain and inflammation, like ibuprofen or naproxen
Pemetrexed
Steroid medications like prednisone or cortisone