Bupropion XL

How should you use this medication?
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Do not cut, crush or chew this medicine. Take your medication at regular intervals. If you take this medication more than once a day, take your second dose at least 8 hours after you take your first dose. To limit difficulty in sleeping, avoid taking this medication at bedtime. Do not take your medication more often than directed. Do not stop taking this medication suddenly except upon the advice of your care team. Stopping this medication too quickly may cause serious side effects or your condition may worsen. A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time. Talk to your care team about the use of this medication in children. Special care may be needed.

What are the possible side effects of this medicine?
Side effects that you should report to your care team as soon as possible:

Allergic reactions-skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Increase in blood pressure
Mood and behavior changes-anxiety, nervousness, confusion, hallucination, irritability, hostility, thoughts of suicide or self-harm, worsening mood, feelings of depression
Redness, blistering, peeling, or loosening of the skin, including inside the mouth
Seizures
Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Constipation
Dizziness
Dry mouth
Loss of appetite
Nausea
Tremors or shaking
Trouble sleeping

What may interact with this medicine?
Our pharmacists will check to see if this medication will cause any interactions with the information in your profile.
Do not take this medication with any of the following:

Linezolid
MAOIs like Azilect, Carbex, Eldepryl, Marplan, Nardil, and Parnate
Methylene blue (injected into a vein)
Other medications that contain bupropion like Zyban This medication may also interact with the following:
Alcohol
Certain medications for anxiety or sleep
Certain medications for blood pressure like metoprolol, propranolol
Certain medications for depression or psychotic disturbances
Certain medications for HIV or AIDS like efavirenz, lopinavir, nelfinavir, ritonavir
Certain medications for irregular heart beat like propafenone, flecainide
Certain medications for Parkinson’s disease like amantadine, levodopa
Certain medications for seizures like carbamazepine, phenytoin, phenobarbital
Cimetidine
Clopidogrel
Cyclophosphamide
Digoxin
Furazolidone
Isoniazid
Nicotine
Orphenadrine
Procarbazine
Steroid medications like prednisone or cortisone
Stimulant medications for attention disorders, weight loss, or to stay awake
Tamoxifen
Theophylline
Thiotepa
Ticlopidine
Tramadol
Warfarin